Description
SS-31 (Elamipretide) – Research Peptide
SS-31 (also known as Elamipretide) is a mitochondria-targeted peptide studied for its ability to interact with cardiolipin within the inner mitochondrial membrane. In research environments, SS-31 is investigated for its potential role in mitochondrial efficiency, cellular energy regulation, and oxidative stress modulation.
This peptide has attracted interest in laboratory studies involving mitochondrial biology, metabolic research, and models of cellular stress where mitochondrial function plays a central role.
AlphaGrade Peptides provides SS-31 in high-purity research format for laboratory and analytical applications.
Research Overview
SS-31 belongs to a class of mitochondria-targeting peptides designed to selectively localize to mitochondrial membranes. Unlike many compounds that affect mitochondrial signaling indirectly, SS-31 has been shown in studies to bind cardiolipin, a phospholipid unique to the inner mitochondrial membrane.
Cardiolipin plays a key role in mitochondrial structure, electron transport chain stability, and ATP production. Through interaction with cardiolipin, SS-31 is investigated for its potential to support mitochondrial membrane integrity and improve electron transport efficiency in laboratory models.
Because mitochondrial dysfunction is linked to numerous cellular processes, SS-31 has become a subject of interest across multiple fields of biological research.
Areas of Scientific Investigation
Research models involving SS-31 commonly focus on:
• Mitochondrial bioenergetics
• Cellular energy production (ATP synthesis)
• Oxidative stress and reactive oxygen species (ROS)
• Cardiolipin stabilization within mitochondrial membranes
• Cellular resilience in metabolic stress models
• Age-related mitochondrial decline research
These areas make SS-31 a valuable compound in experimental studies examining the role of mitochondria in systemic cellular function.
Mechanism of Interest (Research Context)
In laboratory studies, SS-31 has demonstrated the ability to:
• Selectively localize to mitochondria
• Bind cardiolipin within the inner mitochondrial membrane
• Support electron transport chain efficiency in experimental models
• Reduce mitochondrial reactive oxygen species generation in controlled environments
This mitochondrial targeting ability distinguishes SS-31 from compounds that influence cellular energy indirectly.
Research Applications
SS-31 is frequently utilized in laboratory investigations involving:
• mitochondrial biology
• cellular metabolism studies
• oxidative stress models
• metabolic dysfunction research
• age-related cellular studies
• cardiometabolic experimental models
Because mitochondrial function underpins many biological systems, SS-31 remains an important tool in mitochondrial research.
Product Specifications
Compound: SS-31 (Elamipretide)
Category: Mitochondrial Research Peptide
Purity: ≥99% (HPLC)
Format: Lyophilized powder
Stability: Stored refrigerated prior to reconstitution
Each vial is manufactured under strict laboratory quality standards to ensure purity, consistency, and reliability for research environments.
Storage
For maximum stability:
• Store refrigerated at 2–8°C
• Protect from light and excessive heat
• After reconstitution, maintain refrigerated storage and minimize freeze-thaw cycles
Research Use Notice
This product is intended for laboratory research purposes only.
Not for human consumption.
Not for therapeutic or diagnostic use.
Not intended to diagnose, treat, cure, or prevent any disease.





